In the top of the second inning, Seiya Suzuki reached first base on a throwing error by Tim Anderson to get the frame going.
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Facing a 2-2 count, Christopher Morel then did his part, smashing a home run to center field to extend the Cubs’ lead. The ball left his bat at 104.7 miles per hour, and had an expected batting average of .850, according to MLB Statcast.
The Cubs entered the Crosstown Classic with a seven-game deficit in the standings, though they have the best run-differential in the National League Central and a 6-4 record in their last 10 games.
The White Sox meanwhile are 12.5 games back in the American League Central with a 41-60 record on the campaign.